All posts by dallas

Indian Pharma Manufacturing Industry

India today contributes about 22 per cent of the total generic production by volume, third largest exporter of pharma and 11th largest manufacturer by value. There was an inflection point so far in the history of Indian pharma during COVID-19 in 2020 which had positive outcomes for the pharma industry. It was an opportunity to not only cater to the Indians but to the entire world”.’Indian pharma will contribute to play a similar kind of role going forward”.Indian pharma is at the forefront of  tackling non-communicable diseases (NCDs) and emerging diseases with the understanding of technology and disease patterns as Indian pharma did in the case of developing vaccines for COVID-19 and also repurposed drugs for the same. “Indian pharma has crossed the rubicon of being the generic pharma producer in the world and therefore should look beyond as digitilisation will take it much ahead”,

“The Department of Pharmaceuticals (DoP) has launched schemes like bulk drug parks and has issued entrepreneurship and innovation policy guidelines.It should, therefore, adopt innovation hubs with all the players’ like researchers, hospitals, academia, regulators, manufacturers and technology players at one place as is done in the west. The Centre will also encourage industry to invest in specific priority areas and there will centres of excellence for both pharma and medical devices going forward,”

Can The G20 Summit 2023 Be The Catalyst?

The G20 summit is an important platform for world leaders to come together and address major healthcare issues, including universal health coverage (UHC) and more robust health systems to respond to global health emergencies. One area where India has the potential to play a leading role in the G20 is the use of digital technologies to enhance primary healthcare.

As India assumes the G20 presidency in 2023, actions must reflect the need of the hour – to promote a human-centric approach to technology, encourage increased knowledge sharing in critical sectors like digital public infrastructure, and strongly emphasize digital health. In addition, AI technologies will be essential for incidental case finding and monitoring as we work to reimagine post-pandemic primary healthcare.

Adopting a multi-pronged approach is essential, focusing on early detection, diagnosis, and treatment of TB and addressing poverty, malnutrition and uneven healthcare access. With a concerted effort and collaboration, we can work towards a TB-free India by 2025.

Anti Viral Agents

Bengaluru-based Foundation for Neglected Disease Research (FNDR) and Spanish firm DevsHealth have announced the start of a collaborative project to develop new broad-spectrum antiviral agents for infections caused by flaviviruses such as dengue, Zika,West Nile virus, and Japanese encephalitis, among others. Flaviviruses belong to the Flaviviridae family of viruses and cause more than 400 million human infections per year. Most cases are
mild infections with self-limiting febrile episodes, but some infections cause severe and life-threatening disease with symptoms such as haemorrhagic fever, encephalitis, paralysis, or hepatic failure, among others.

Climate change is affecting global disease distribution, and an increase in flavivirus infection cases has been seen in Europe and North America. This collaboration has the potential to revolutionise the way flavivirus infections are treated. There are currently no drugs available to patients to treat these infections.

Tuberculosis In India

Tuberculosis (TB) is a severe public health issue in India,accounting for a quarter of the global TB burden. While the World Health Organisation (WHO) has set a goal to end the TB epidemic by 2030, India committed to ending the disease by 2025, a mission backed by Prime Minister Narendra Modi. But the crucial question here is whether it is an achievable target? According to the WHO, only 60 per cent of TB cases in India are notified to the national TB programme. Incidentally, most patients do not seek medical attention at all or are not diagnosed until the disease is in its advanced stages. At this juncture, technology comes in to assist in early and better TB detection. Early detection is a key strategy called out in the Global Plan to End TB.

Challenges on the road

Despite technological advancements, numerous challenges remain in the fight against TB in India. One of the biggest is the lack of access to healthcare in rural and remote locations. Many people in these areas do not have access to the same resources and technology as those living in urban areas. They may not have the necessary awareness to seek medical attention in time; even if they do, the plight of Primary Health Centres (PHCs) in rural locations abates the situation. The PHCs do not have access to diagnostic tools and suffer from a severe shortage of trained personnel to read reports and guide patients onto the correct treatment pathway. All of these factors, coupled with the rising cost of care, make diagnosing and treating TB significantly tougher. Another challenge is the high number of drug-resistant TB cases in India. This type of TB is much harder to treat and requires more expensive, specialised drugs and a longer duration of treatment. Lack of research and an inability to implement measures to cap the treatment and drug costs are aiding the spread of the epidemic.

Though India has a detailed National Strategic Plan for TB elimination, its efficient execution depends on the State Health System. Indian states are at varied maturity levels in the health system, so TB service delivery also varies. In many places, it is affected by a lack of skill set to deliver TB services. While the Government of India focus on decentralised,comprehensive Primary Healthcare delivery is now bearing fruit, it will take more time to implement effectively and become a well-
oiled system.

Swine Flu Claim 736 Lives This Year

As many as 736 persons have died due to the deadly H1N1 virus in India since January this year, latest data from Union Health Ministry reveals. Up to 15,121 persons have been infected with the virus until July 30 this year.

Maharashtra has the largest number of infections, up to 3,450, and has recorded the most deaths up to 358. Following close on its heels is Gujarat with 549 cases and 107 deaths.

While 70 persons died of swine flu in Kerala (1,285 cases) this year, 59 persons died in Rajasthan (422 cases), and 15 succumbed in Karnataka (2,732 cases).

“Every few years, the virus mutates. While in 2009-10 it was a deadly blow and had been declared pandemic, over the years its potency has reduced,” said a health ministry official.

The official stated that there is an antigenic drift over the years where the virus naturally mutates over time. “And every few years there is also an antigenic shift, which will see a different virus emerging to be pandemic, than the one we had seen a few years ago.”

An antigenic shift will involve mutations in the virus which will lead to loss of immunity in the masses for the new mutations and will also cause a vaccine mismatch.

Dengue Update – Maintenance And Caution

As advised by Medical Professionals we would like to share some valuable information which shall be very helpful to all patients who start getting early symptoms of  Dengue, but can be helpful in maintainance without cause for undue alarm.

1. Once infection occurs, one can get fever within 1- 7 days.

2. Fever, usually high, comes daily for 4-5 days.This time is troublesome due to fever & body aches. At this time, patient should be given lots of fluids, water, juice, cold drinks, tea, milk or soup any thing can be given. Just keep patient well hydrated. One simple way is to see tongue. It should appear wet.Also patient should pass adequate urine.  Some people will not be able to drink adequate fluids , due to vomiting, pain abd, or just apathy for any thing orally. If patient can’t take enough orally, and his urine output is getting less & lesser, this is an indication that patient should be admitted for intravenous fluids. Pl take him to nearby hospital. One important thing to remember is , the blood test should be done early in the fever, but rather than PLT count, at the fever stage we should see HB level. It should be within normal basal limit of that patient. If u find HB is high , it is a danger sign, even if PLT count is normal. Most of people including doctors wait for PLT count to fall, & keep waiting, telling patient not to worry as PLT count is normal. But this is wrong. Recent rise of HB should not be overlooked. If it is 14 or more , we need to give fluids very rapidly, oral as well as i.v. to bring down HB level to basal level. So do not wait for PLT count to fall, take action when HB has gone up, even when PLT are in normal range.

Next stage starts when fever becomes normal. At this stage, patient feels better, but PLT count is likely to progressively go down. Still, we need not worry due to falling PLT count. A count upto 10,000 is certainly safe, unless patient has active bleeding. There is no role of PLT transfusions in a patient, who has no active bleeding. So pl do not insist for PLT transfusions in the absence of bleeding.

So friends, let us remember,

1. Once patient has fever, start plenty oral fluids, ( appx. 3-4 litres in an adult,& proportionate in children).

2. Give Paracetamol for fever. No aspirin/ brufen/ numulid etc.

3. Monitor for breathless during this period, especially when patient does not have fever. If patient complains of breathless ness, when he is afebrile, take him to a doctor. This is important symptom & indicates SEVERE infection, Iikely to worsen. DO NOT OVERLOOK BREATHLESSNESS, especially WHEN patient DOES NOT HAVE FEVER.

4. Once fever settles, this is the time when PLT count will fall further. But do not panic, most PTS will recover without complications, just be in touch with a doctor.

5. With best wishes for a dengue free India.

Prevent Swine Flu – Good Advice

Dr. Vinay Goyal is an MBBS,DRM,DNB (Intensi invist and Thyroid specialist) having clinical experience of over 20 years. He has worked in institutions like Hinduja Hospital, Bombay Hospital, Saifee Hospital, Tata Memorial etc. Presently, he is heading our Nuclear Medicine Department and Thyroid clinic at Riddhivinayak Cardiac and Critical Centre, Malad (W).

The following message given by him, I feel makes a lot of sense and is important for all to know.

The only portals of entry are the nostrils and mouth/throat. In a global epidemic of this nature, it’s almost impossible to avoid coming into contact with H1N1 in spite of all precautions. Contact with H1N1 is not so much of a problem as proliferation is.

While you are still healthy and not showing any symptoms of H1N1 infection, in order to prevent proliferation, aggravation of symptoms and development of secondary infections, some very simple steps, not fully highlighted in most official communications, can be practiced (instead of focusing on how to stock N95 or Tamiflu):

1. Frequent hand-washing (well highlighted in all official communications).

2. “Hands-off-the-face” approach. Resist all temptations to touch any part of face (unless you want to eat, bathe or slap).

3. * Gargle twice a day with warm salt water (use Listerine if you don’t trust salt)… * H1N1 takes 2-3 days after initial infection in the throat/ nasal cavity to proliferate and show characteristic symptoms. Simple gargling prevents proliferation. In a way, gargling with salt water has the same effect on a healthy individual that Tamiflu has on an infected one. Don’t underestimate this simple, inexpensive and powerful preventative method.

4. * Similar to 3 above, * clean your nostrils at least once every day with warm salt water. * Not everybody may be good at Jala Neti or Sutra Neti (very good Yoga asanas to clean nasal cavities), but * blowing the nose hard once a day and swabbing both nostrils with cotton buds dipped in warm salt water is very effective in bringing down viral population.

5. * Boost your natural immunity with foods that are rich in Vitamin C (Amla and other citrus fruits). * If you have to supplement with Vitamin C tablets, make sure that it also has Zinc to boost absorption.

6. * Drink as much of warm liquids (tea, coffee, etc) as you can. * Drinking warm liquids has the same effect as gargling, but in the reverse direction. They wash off proliferating viruses from the throat into the stomach where they cannot survive, proliferate or do any harm. I suggest you pass this on to your entire e-list. You never know 20 who might pay attention to it – and STAY ALIVE because of it…

Launching Soon : DD3 ( Injection / 6 LAC IU)


We are soon launching one of the most needful products of present times i.e cholecalciferol in high strengths both in table as well as injectable form by the name of DD3 Our focus thus is to strengthen the musco-skeletal system of our countrymen right from childhood, to old age in males as well as females. DD3 Injection containing cholecalciferol 6 Lac units.

Launching Soon : DD3 ( Tablet Vitamin D3 / 60,000 IU )

We are soon launching one of the most needful products of present times i.e cholecalciferol in high strengths both in table as well as injectable form by the name of DD3 Our focus thus is to strengthen the musco-skeletal system of our countrymen right from childhood, to old age in males as well as females. DD3 Chewable teblets containing cholecalciferol 60,000 units.